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Tag Archives: Erectile Dysfunction management

Diabetes and Erectile Dysfunction – Erection to Fight Dejection

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ShareSildenafil (Viagra) was the first oral treatment for ED. It selectively inhibits phosphodiesterase-5 (PD-5), an enzyme that breaks down intracellular cyclic guanosine monophosphate (GMP). This causes smooth muscle relaxation and improves penile blood flow. It is effective in the presence of sexual stimulation but does not cause spontaneous erections or increased libido. Subsequently, the other PD-5 inhibitors, vardenafil and tadalafil, …

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